With the increasing requirements for experimental environment, how to high-level disinfection to ensure the normal development of experiments and research, to prevent the occurrence of sample contamination, and to better protect researchers, more and more attention has been paid. Traditional ultraviolet lamp and ozone formaldehyde fumigation method have big defects, it is urgent to find a more safe and reliable disinfection and sterilization method.
Hydrogen peroxide space sterilization technology is an efficient, non-toxic and non-residual sterilization method, which has been widely used in pharmaceutical and biosafety industries abroad, instead of traditional ultraviolet lamp or ozone, formaldehyde fumigation and other disinfection and sterilization methods. Its main advantages are: high sterilization efficiency, very safe to personnel, zero residue to the environment, is an ideal alternative to environmental disinfection and sterilization technology.
Principle of action:
The 2010 edition of “GMP Guidelines for sterile drugs” page 418~419, this sterilization principle has a detailed introduction, has no formaldehyde fumigation content.
Sterilization is accomplished by spraying the area to be sterilized with a dry mist. When the average diameter of the droplets is less than 10 microns, the fog emitted is said to be “dry”, so it is called “dry fog”.
Dry fog has the following characteristics:
- Dry fog droplets (grains) do not settle and move irregularly (Brownian motion principle);
- Dry fog droplets do not coalesce to produce large droplets;
- Dry fog droplets will rebound upon contact with the surface without breaking and wetting the surface;
These characteristics determine that it has a good diffusion effect, making difficult to reach places also have a good space and surface contact effect.